Clinical Laboratory Technician

Sobre a vaga

The Cell Centre is looking to expand efforts in the GMP production of cell products with a specific focus on immune-monitoring. The successful applicant is expected to be pivotal co-worker in the development and improvement of immune cell-based therapies for malignant diseases and the preparation of GMP compliant production of cellular products including gene-modified immune cells and monitoring of anti-cancer directed vaccination. Duties & Responsibilities - Lab management and organisation with an excellent team and collaborative spirit within the institution and with our international partners; - Close interaction with clinical colleagues and within immunotherapeutic programs; - Analysis and interpretation of immune responses; - Procurement of clinical samples and subsequent processing for molecular and functional analysis; - Procurement of cellular products for (non-vector and vector-based) therapy; - Excellent expertise in in tissue culture; - Advanced flow cytometric analyses; - Excellent knowledge or dedication to acquire strong skills in QC documentation. Qualifications & Skills - Strong knowledge in human T-cell and B-cell biology and immunology; - Documented and well advanced practical and theoretical knowledge in cellular analysis and immunological assays to gauge cellular and humoral immune responses; - Previous work experience with lentiviral (LV) and non-LV based gene transfer is a plus; - Skills in DNA and RNA processing; - Very good knowledge in molecular technologies, excellent knowledge in flow cytometry, T-cell sorting and gauging immune effector functions; - Team spirit and will to collaborate within the foundation and with our partner institutions with the possibility to travel for clinical, international projects; - Fluency in English and excellent communication skills (written and verbal) in English. Requirements - Research Field: Biological sciences » Other - Education Level: Master Degree or equivalent How to apply To apply, please send a letter of motivation, a 2-page CV and the names and contact information of 2 references to [email protected] with “Laboratory technician [your last name]” in the subject line. Position will remain open until filled. About Us Research is at the heart of the Champalimaud Centre for the Unknown, a modern research and clinical facility situated on the waterfront in Lisbon, Portugal. Champalimaud Research comprises a team of over 250 scientists from around the world with foci in neuroscience and cancer research with a strong development in the production of cell therapy products. English is the official language of the Centre. Lisbon’s sunny Atlantic-Mediterranean climate, vibrant culture and high quality of life make this a great place to live and work.

O que procuramos

• The Cell Centre is looking to expand efforts in the GMP production of cell products with a specific focus on immune-monitoring.
• The successful applicant is expected to be pivotal co-worker in the development and improvement of immune cell-based therapies for malignant diseases and the preparation of GMP compliant production of cellular products including gene-modified immune cells and monitoring of anti-cancer directed vaccination.
• Duties & Responsibilities
• Lab management and organisation with an excellent team and collaborative spirit within the institution and with our international partners;

Responsabilidades

• The Cell Centre is looking to expand efforts in the GMP production of cell products with a specific focus on immune-monitoring.
• The successful applicant is expected to be pivotal co-worker in the development and improvement of immune cell-based therapies for malignant diseases and the preparation of GMP compliant production of cellular products including gene-modified immune cells and monitoring of anti-cancer directed vaccination.
• Duties & Responsibilities
• Lab management and organisation with an excellent team and collaborative spirit within the institution and with our international partners;
• Close interaction with clinical colleagues and within immunotherapeutic programs;